Cancer-specific Therapeutic Potential of Resveratrol: Metabolic Approach against Hallmarks of Cancer

Authors

  • Dong Hoon Suh Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam
  • Mi-Kyung Kim Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul
  • Hee Seung Kim Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul
  • Hyun Hoon Chung Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul
  • Yong Sang Song Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul

DOI:

https://doi.org/10.31989/ffhd.v3i8.44

Abstract

Cancer hallmarks include evading apoptosis, limitless replicative potential, sustained angiogenesis, tissue invasion and metastasis. Cancer cells undergo metabolic reprogramming and inevitably take advantage of glycolysis to meet the increased metabolic demand: rapid energy generation and macromolecular synthesis. Resveratrol, a polyphenolic phytoalexin, is known to exhibit pleiotropic anti-cancer effects most of which are linked to metabolic reprogramming in cancer cells. This review summarizes various anti-cancer effects of resveratrol in the context of cancer hallmarks in relation to metabolic reprogramming.

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Published

2013-08-26

Issue

Vol. 3 No. 8 (2013): August 2013

Section

Review Articles

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