Exploring the potential of bioactive compounds in preventing cancer growth and progression: A comprehensive review

Authors

  • Mohammad Foroughi-Gilvaee
  • Danik Martirosyan
  • Mohammad Mashayekhnia
  • Mohammad Maadi
  • Mohammad Sarvendani
  • Maryam Maghsoumi

DOI:

https://doi.org/10.31989/bchd.v7i6.1370

Abstract

Cancer stands as a prominent global cause of mortality, with a noteworthy surge in related deaths in recent years. Over the past decade, several bioactive compounds have emerged as potent agents in impeding the relentless advance of cancer. Notably, numerous studies highlight the efficacy of natural plant-derived bioactive compounds in augmenting chemotherapy outcomes and mitigating adverse drug effects associated with chemotherapeutic agents. This comprehensive review investigates the anticancer effects of three types of bioactive compounds: polyphenols, alkaloids, and terpenoids. It elucidates their mechanisms of action and consolidates evidence from preclinical studies. Furthermore, this review delves into the molecular mechanisms through which these active compounds may manifest their anticancer properties, drawing insights from cell and animal-based studies.

Keywords:  Bioactive compounds, cancer prevention, polyphenols, alkaloids, terpenoids

Downloads

Published

2024-06-26

Issue

Vol. 7 No. 6 (2024): June 2024

Section

Review Articles

License

Copyright (c) 2024 FFC/Bioactive Compounds in Health and Disease

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Authors retain the copyright of their articles and grant the Functional Food Center (FFC) and its journals the right of first publication under the terms of the Creative Commons Attribution 4.0 International License.

This license permits unrestricted use, distribution, and reproduction in any medium, including commercial use, provided the original author(s) and source are properly credited. Authors may post and share their published work freely, provided that the original publication in this journal is acknowledged.

By submitting to this journal, authors confirm that their manuscripts are original, not under consideration elsewhere, and that they hold the necessary rights to grant this license. The Functional Food Center encourages open scientific exchange and allows derivative and extended works, provided attribution to the original publication is maintained.