Georgian legume crop extract as an effective remedy during oral cavity soft tissue inflammation

Tamar Sanikidze, Irakli Chkhikvishvili, Nana Kipiani, Samson Mghebrishvili, Irina Barbakadze, Nino Komakhidze, Tinatin Maminaishvili, Eka Shekiladze, Sophio Japaridze

Abstract


Background: Recovery of dental arch defects, related to insertion of a foreign bodies into the oral cavity, and the impact of mechanical pressure, allergic-toxic effects, and the related inflammatory and degenerative processes is one of the most urgent problems in dentistry.

The purpose of the study was to evaluate the efficacy of Georgian bean extract tincture as mouthwash for patients using a lever system to correct deformities of the jaw and teeth.

Methods: Twenty-eight patients (aged 12-25 years) with deformities of the jaw and teeth were studied. Patients were examined 6-8 months after the bracket system was installed, and before and after the use of tincture mouthwash for 10 days. Patients were randomly divided into 2 groups: the control group for the mouthwash used standard tincture ("Octenidol" Schulke and Mayr -Germany); the patients of the experimental group used tincture made from the Georgian legume crop extracts (GLCE). Before and after the use of both types of tincture, the data were taken for calculation of Schiller Pisarev's test (SPT), Papillary-Marginal Alveolar (PMA) index, and the oral hygiene index (OHI). Saliva was collected in a glass tube without stimulation, on an empty stomach. The content of cytokines IL-1β, IL-10 in saliva was determined by the ELISA kit.

Results: The study demonstrated significant positive clinical efficacy of the mouthwash tincture prepared from the GLCE which increases the resistance of dental tissue. This was revealed by significantly lower values of OHI, PMA index, SPT and increased content of IL-10 in saliva.

This data indicates that tincture prepared from the Georgian legume crop extracts, which is designed to increase the stability of oral tissue, does promote an increase in resistance to the aggressive mechanical pressing.

Conclusion: Tincture from the GLCE is characterized by a much stronger anti-inflammatory effect than standard tincture "Octenidol" (Schulke and Mayr -Germany) used against inflammation of the oral cavity soft tissue. This allows us to recommend the tincture from the GLCE for the treatment and prevention of inflammatory processes in the oral cavity soft tissue.

Keywords: Georgian legumes crop extracts (GLCE), oral cavity soft tissue inflammation, Hygiene Index, PMA index, Schiller Pisarev's test.


Full Text: [Abstract] [Full Article]

DOI: 10.31989/ffhd.v10i1.678

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Copyright (c) 2020 Tamar Sanikidze, Irakli Chkhikvishvili, Nana Kipiani, Samson Mghebrishvili, Irina Barbakadze, Nino Komakhidze, Tinatin Maminaishvili, Eka Shekiladze, Sophio Japaridze

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